HIGH-ABSORPTION BERBERINE HCL
FOR OPTIMAL 
HEALTH BENEFITS

FORMULATED TO HELP

  • SUPPORT WEIGHT MANAGEMENT
  • OPTIMIZE GLUCOSE METABOLISM
  • REDUCE CHOLESTEROL & BLOOD SUGAR LEVELS
  • IMPROVE GUT FLORA & BALANCE BACTERIA
  • FIGHT INFLAMMATION & PROVIDE ANTIOXIDANTS
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Bottles of Approved Science high-absorption berberine HCL with BioPerine for optimal health benefits and vegan-friendly formula.

WHAT IS APPROVED SCIENCE® BERBERINE?

A TOP-QUALITY, HIGHLY ABSORBABLE BERBERINE SUPPLEMENT

Scientists in lab with text: improve blood health, decrease bad bacteria, boost antioxidants for berberine HCL benefits.Scientists in lab with text: improve blood health, decrease bad bacteria, boost antioxidants for berberine HCL benefits.

APPROVED SCIENCE® BERBERINE

is an expertly-crafted Berberine supplement that has been formulated with high-quality ingredients such as BerineAbsorb™ which contains 1000 mg Berberine HCL as well as 5 mg BioPerine® to enhance absorption and deliver faster results. Approved Science® Berberine has been studied and produced in a top-quality, cGMP-certified and FDA-licensed laboratory environment under the most rigorously professional conditions.

The positive benefits of the ingredients found in Approved Science® Berberine have been published by organizations such as Biochemistry and Cell Biology, Evidence-Based Complementary and Alternative Medicine, and the Chinese Journal of Integrative Medicine.

Approved Science® Berberine - research drives results!

WHY CHOOSE APPROVED SCIENCE® BERBERINE

TO IMPROVE CARDIOVASCULAR AND GUT HEALTH?

No other Berberine supplements contain BerineAbsorb™, a unique form of Berberine HCl fused with BioPerine® to enhance absorption. An absorption aid is especially important because Berberine has naturally low absorption. Many other products do not contain 1000 mg of Berberine which helps with improving glucose utilization, balancing blood sugar and cholesterol levels, and enhancing gut health. Many products are also non-vegan, even though Berberine itself is. The truth is that most Berberine supplements do not live up to consumer standards. Most do not have the potency needed. And most contain ingredients such as unnecessary proprietary blends, additives, preservatives, fillers, or binders.

Due to extensive research and our firm understanding of what makes an effective Berberine supplement, we have created a product that is uniquely formulated to provide the ultimate blood sugar, cholesterol, and gut support.

Each ingredient was carefully selected, based on years of research and clinical studies. Over 20 years of safety and efficacy research has been documented on how to formulate a quality Berberine supplement to get the very best results possible.

Approved Science Berberine HCL bottle with icons highlighting high absorption, gut health, blood sugar support, and wellness benefits.Approved Science Berberine HCL bottle with icons highlighting high absorption, gut health, blood sugar support, and wellness benefits.

APPROVED SCIENCE® BERBERINE IS THE  #1 CHOICE FOR QUALITY & EFFECTIVENESS

Comparison of high-absorption berberine HCl with BerineAbsorb vs. other brands, showing dosage, absorption, and vegan status.Comparison of high-absorption berberine HCl with BerineAbsorb vs. other brands, showing dosage, absorption, and vegan status.
Doctors reviewing health data with benefits of high-absorption berberine HCL: regulate metabolism, antioxidant, reduce cholesterol, lessen triglycerides.Doctors reviewing health data with benefits of high-absorption berberine HCL: regulate metabolism, antioxidant, reduce cholesterol, lessen triglycerides.

THE BENEFITS

OF BERBERINE

  • Blue check mark.

    Helps regulate metabolism and improve insulin resistance to lower blood sugar levels

  • Blue check mark.

    Slows the breakdown of carbs into sugar and decreases sugar production in the liver

  • Blue check mark.

    Antioxidant, anti-inflammatory, and antimicrobial effects help to protect organs

  • Blue check mark.

    Nourishes good bacteria in the gut for a better bacterial balance

  • Blue check mark.

    May reduce LDL cholesterol and triglycerides for better blood flow

HOW DOES

APPROVED SCIENCE® BERBERINE WORK?

A white bottle labeled Berberine with gold accents.

Approved Science® Berberine provides 1000 mg of Berberine HCl which is a high dosage, but not too high since excessive doses of Berberine are more likely to cause toxicity and gastrointestinal upset. To improve absorption, our formula contains BioPerine® which is a thermogenic bioavailability enhancer - meaning it delivers faster and better results. The ingredients contained in Approved Science® Berberine were selected by a team of doctors and scientific researchers based on clinical data and designed to get results more effectively than other Berberine supplement available.

This unique supplement provides BerineAbsorb Bioavailable Berberine, the ultimate formula to optimize the absorption and benefits of Berberine. Many studies document the positive benefits of Berberine HCl supplements for improving blood sugar levels as well as blood pressure, cholesterol levels, and gut health.

This  top quality Berberine supplement provides many incredible benefits. These include the ability to  Activate, Fight, Reduce, and Balance, making this an excellent product that contributes towards better cardiovascular health, while also benefiting the gut.

In terms of quality and purity of ingredients, there is nothing else on the market that comes close to Approved Science® Berberine.

  • Red blood cells and white cubes inside a blue circle.

    STEP #1 ACTIVATE

    Berberine activates AMPK which is an enzyme inside the body’s cells that regulates cellular energy. This enzyme is the “metabolic master switch” that determines if cells need to produce more energy, and whether they need more sugar. Therefore, Berberine helps the body to effectively use sugar.

  • Molecular structure with orbiting electrons.

    STEP #2 FIGHT

    Berberine has anti-inflammatory and antioxidant benefits. It is also believed to fight harmful microorganisms in the body and can reduce bacteria, viruses, fungi, and parasites.

  • Red heart with white heartbeat line in center.

    STEP #3 REDUCE

    Clinical studies indicate that Berberine may have a beneficial effect on cholesterol levels by inhibiting cholesterol absorption in the intestines which then reduces LDL cholesterol in the blood. Similarly, Berberine helps lower triglycerides and low-density lipoproteins. These effects improve cardiovascular health and help to prevent heart-related diseases.

  • Human digestive system organs cross-section.

    STEP #4 SUPPORT

    Berberine has been found to increase good bacteria in the gut, in this case, the bacteria that produces short-chain fatty acids. This type of bacteria also helps protect against pathogens and mitigate inflammation. This has a positive effect on digestion and helps to improve nutrient absorption.

APPROVED SCIENCE® BERBERINE FORMULA

CLINICALLY SUPPORTED INGREDIENTS PROVEN TO OPTIMIZE GUT AND BLOOD HEALTH

INGREDIENTS

Approved Science Berberine HCL with BioPerine, GMP certified, high-absorption capsules for optimal health benefits.Approved Science Berberine HCL with BioPerine, GMP certified, high-absorption capsules for optimal health benefits.
  • Cluster of red berberine berries.

    BERINEABSORB™ BIOAVAILABLE BERBERINE

    Contains Berberine HCl which is known for having positive effects on blood sugar levels, blood pressure, cholesterol, and gut health. To improve absorption and optimize results, this blend includes BioPerine® which is a patented extract of black pepper that has thermogenic effects.

  • Green vegan product label with leaf icon.

    VEGAN

    Contains no animal products or by-products.

  • Green checkmark for tested and certified approval.

    CERTIFIED

    Manufactured in the USA in an FDA-recognized and cGMP-approved facility.

HOW DOES APPROVED SCIENCE® BERBERINE COMPARE?

A white bottle labeled Berberine with gold accents.A white bottle labeled Berberine with gold accents.

APPROVED SCIENCE® BERBERINE

White Berberine HCl supplement bottle with label.White Berberine HCl supplement bottle with label.

BIOTICS RESEARCH BERBERINE HCL

Dr. Mercola Berberine and MicroPQQ supplement bottle.Dr. Mercola Berberine and MicroPQQ supplement bottle.

DR. MERCOLA'S BERBERINE AND MIRCOPQQ ADVANCED

White bottle labeled berberine dietary supplement.White bottle labeled berberine dietary supplement.

PHYSICIAN'S HEALTHY ALTERNATIVES BERBERINE

White bottle labeled Berberine HCL dietary supplement.White bottle labeled Berberine HCL dietary supplement.

XYMOGEN BERBERINE

Contains 1000 mg Berberine Per Serving

YES

NO

NO

YES

YES

Contains BioPerine® For Improved Nutrient Absorption

YES

NO

NO

NO

NO

Vegan-Friendly

YES

NO

NO

YES

YES

Made In An GMP-Certified Lab

YES

YES

YES

YES

YES

60-Day 100% Money-Back Guarantee

YES

NO

YES

NO

NO

Recommended Choice

Yellow check mark inside a black circle.Yellow check mark inside a black circle.

What's THE WORD ON Approved Science® Berberine?

If you're ready, join the thousands of Americans who have already experienced the benefits and seen the results!

Who would have thought two simple pills a day could do so much. I regularly check my blood sugar and it's been too high lately which is what prompted me to buy this product. My last blood test showed improvement and I'm glad to finally be seeing results.

Howie H

This has significantly helped with my PCOS. Symptoms have improved. Will buy again.

Susan B

My husband has seen tremendous results with this product. His A1C has improved, his energy levels are higher, and he's even lost a pound or two.

Reese V

I wasn't responding to treatment with statins so my doctor recommended that I take Berberine to lower my cholesterol. I ordered a three month package because I can't ignore a deal but I wasn't sure that I'd be taking the product for 6 months either. I finished the whole package and I'm taking off a...

Ryan D

I took this product to lower my blood sugar and was pleasantly surprised to see lower numbers not only on my test but also on the scale!

Lidia R

I never really believed in supplements much but my doc recommended that I try Berberine and I trust his expert opinion. My A1C has gone down by over a whole point! I'm amazed.

Ron H

I love that this brand makes Berberine now. I rely on Approved Science for all my supplement needs so now that they've added Berberine, I've added it to my cart. I've been taking Berberine for a few weeks, 6 days a week, and it keeps my blood sugar levels down as can be expected. Satisfied.

Ailen S

I did have some stomach upset in the beginning as I got used to taking Berberine but it was worth it. My cholesterol levels have improved, my blood pressure is better, and my blood sugar is closer to normal.

Mark F

Berberine is a complete game changer! I finally feel like my blood pressure and cholesterol are back on track. If you're trying to improve your health, I highly recommend this product.

Mary P

Who would have thought two simple pills a day could do so much. I regularly check my blood sugar and it's been too high lately which is what prompted me to buy this product. My last blood test showed improvement and I'm glad to finally be seeing results.

Howie H

This has significantly helped with my PCOS. Symptoms have improved. Will buy again.

Susan B

My husband has seen tremendous results with this product. His A1C has improved, his energy levels are higher, and he's even lost a pound or two.

Reese V

I wasn't responding to treatment with statins so my doctor recommended that I take Berberine to lower my cholesterol. I ordered a three month package because I can't ignore a deal but I wasn't sure that I'd be taking the product for 6 months either. I finished the whole package and I'm taking off a...

Ryan D

I took this product to lower my blood sugar and was pleasantly surprised to see lower numbers not only on my test but also on the scale!

Lidia R

I never really believed in supplements much but my doc recommended that I try Berberine and I trust his expert opinion. My A1C has gone down by over a whole point! I'm amazed.

Ron H

Risk Free

TRY Approved Science® BerberineRISK FREE!

If at any time you are unsatisfied with a product you purchased from us, you may return any opened & unopened bottles within sixty (60) days for a full refund of the returned bottles, not including shipping.

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The statements made on this website have not been evaluated by the Food & Drug Administration. The FDA only evaluates foods and drugs, not supplements like these products. These products are not intended to diagnose, prevent, treat, or cure any disease. Individual results may vary.

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Copyright © 2025 Approved Science® LLC All rights reserved.

*Results will vary from person to person depending on the individual’s existing health condition, physical lifestyle, and diet. Testimonials and results contained within may not be an implication of future results and are based on the experiences of a few people and you may not have similar results. Always consult your doctor prior to making any dietary changes or starting any nutrition, health control or exercise program. This product is not intended to diagnose, treat, cure, or prevent any disease. The information in this website is not intended as a substitute for medical advice. These statements have not been evaluated by the Food and Drug Administration.